منابع مشابه
Analysis of CDNA Microarray Images
Microarrays are part of a new class of biotechnologies that allow the monitoring of expression levels for thousands of genes simultaneously. Image analysis is an important aspect of microarray experiments, one that can have a potentially large impact on subsequent analyses, such as clustering or the identification of differentially expressed genes. This paper reviews a number of existing image ...
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Some normalization methods assume that the two channels of intensities are related by a constant so that Microarray experiments allow RNA level measurements for many the center of the distribution of the log of the ratio is genes in multiple samples. However, mining the biological information shifted to zero. Chen et al. (1997) proposed an iterative from the large sets of data generated by micr...
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Microarray expression analysis has become one of the most widely used functional genomics tools. Efficient application of this technique requires the development of robust and reproducible protocols. We have optimized all aspects of the process, including PCR amplification of target cDNA clones, microarray printing, probe labeling and hybridization, and have developed strategies for data normal...
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Microarray technology is a powerful approach for genomics research. The multi-step, data-intensive nature of this technology has created an unprecedented informatics and analytical challenge. It is important to understand the crucial steps that can affect the outcome of the analysis. In this review, we provide an overview of the contemporary trend on various main analysis steps in the microarra...
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ژورنال
عنوان ژورنال: Journal of Nippon Medical School
سال: 2001
ISSN: 1345-4676,1347-3409
DOI: 10.1272/jnms.68.411